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为探讨人巨细胞病毒感染对母儿的影响 ,采用ELISA法对 1818例早、中、晚孕期孕妇进行HCMV病原体血清学监测 ,并对部分感染者的羊水、胎盘组织、脐血等采用PCR方法监测HCMV -DNA ,同时采用B超监测胎儿的生长发育及新生儿结局。结果发现早、中、晚孕期孕妇中有 78例为活动性感染 ( 4 3% ) ,并发胎膜早破和早产 17例。新生儿先天感染 2 2例 ( 2 8 2 1% ) ,2例流产、4例畸形、13例头颅B超异常 ,9只耳朵BAEP异常。研究强调人巨细胞病毒在孕妇中的感染较为广泛 ,因此有必要进行孕期筛查 ,对出生于活动性感染孕妇的婴儿应密切随访追踪。
In order to explore the influence of human cytomegalovirus infection on maternal and childbirth, 1818 pregnant women in early, middle and late pregnancy were serologically monitored for HCMV pathogens by ELISA, and amniotic fluid, placental tissue and umbilical cord blood of some infected patients were detected by PCR HCMV-DNA was monitored, and fetal growth and neonatal outcomes were monitored using B-ultrasound. The results showed that 78 cases were active infection in early, middle and late pregnancy (43%), premature rupture of membranes and premature delivery in 17 cases. Neonatal congenital infection in 22 cases (2,821%), 2 cases of abortion, 4 cases of deformity, 13 cases of cranial ultrasound B, 9 ears BAEP abnormalities. The study highlights human cytomegalovirus infection in pregnant women is more extensive, it is necessary for screening during pregnancy, infants born to active infection in pregnant women should be followed up closely.