论文部分内容阅读
为了评价母亲HBsAg阳性儿童乙型肝炎 (乙肝 )疫苗免疫效果 ,寻求加强免疫时机 ,北京市卫生防疫站于 1996～ 1999年连续 4年对 1～ 5岁儿童免疫后效果进行流行病学、血清学的横断面调查。结果显示 :5岁以下儿童抗 -HBs阳性率为 78 6 6 %～80 5 6 % ,抗 -HBs阳性率随年龄增长呈下降趋势 ;5岁以下儿童HBsAg携带率为 3 41%～ 3 5 1% ,未呈现随年龄的增长而上升的趋势。不同地区儿童免疫后效果较一致 ;母亲HBsAg阳性儿童接种乙肝疫苗阻断效果理想 ,儿童HBsAg携带率主要为宫内感染或出生后早期感染。据此建议对该类儿童应在出生后 1～ 2年进行乙肝疫苗加强免疫接种
In order to evaluate the immune effect of hepatitis B (HB) vaccine in mothers with HBsAg-positive children and to seek to strengthen the immunization timing, Beijing Municipal Health and Epidemic Prevention Station conducted epidemiological and serological tests on children aged 1-5 years for four consecutive years from 1996 to 1999 Cross-sectional survey. The results showed that the positive rates of anti-HBs in children under 5 years old ranged from 78 6 6% to 80 5 6%, and the positive rates of anti-HBs showed a decreasing trend with age; the carrying rates of HBsAg in children under 5 years old were 341% to 351 %, Did not show an upward trend with age. Children in different regions have the same effect after immunization; mother HBsAg-positive children have an ideal effect of blocking hepatitis B vaccine, and children with HBsAg carrier rate are mainly intrauterine infection or early postnatal infection. Accordingly, it is suggested that such children should be vaccinated for hepatitis B vaccine 1-2 years after birth