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卡介苗(BCG)或其菌体成分用于实验性肝癌的免疫预防和治疗,国外报道颇多,国内少见,且这些常因给药时间长、剂量大,出现许多毒副作用,而难以推广应用。我们用小剂量卡介苗短期内腹腔注射的方法:对二乙基亚硝胺诱发大鼠肝癌过程,进行了初步观察和分析,结果报道下:
BCG or its bacterial components are used for immunoprophylaxis and treatment of experimental liver cancer. There are many reports abroad and it is rare in China. These drugs often have long-term administration and have large doses. They have many toxic and side effects and are difficult to popularize and apply. We used a short-term intraperitoneal injection of low-dose BCG vaccine: The preliminary observation and analysis of the process of diethylnitrosamine-induced liver cancer in rats was performed. The results are reported below: