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目的观察丹红注射液联合硫辛酸注射液冶疗早期糖尿病肾病(DN)的临床疗效。方法将59例早期DN患者分为两组,治疗组应用丹红注射液和硫辛酸注射液联合治疗,对照组应用硫辛酸注射液治疗。比较两组患者在治疗前后尿微量白蛋白及血脂各项主要指标(TC、TG、LDL-C)的变化。结果两组患者尿微量白蛋白及血脂各项指标(TC、TG、LDL-C)均有好转,治疗组尿微量白蛋白明显下降(P<0.05)。治疗组改善效果明显优于对照组(P<0.05)。结论丹红注射液联合硫辛酸注射液治疗早期糖尿病肾病疗效显著,而且效果优于单用硫辛酸注射液。
Objective To observe the clinical efficacy of Danhong injection and lipoic acid injection in the treatment of early diabetic nephropathy (DN). Methods 59 patients with early DN were divided into two groups. The treatment group was treated with Danhong injection and lipoic acid injection, while the control group was treated with lipoic acid injection. The changes of major indexes (TC, TG, LDL-C) of urinary albumin and blood lipid in two groups before and after treatment were compared. Results Urine microalbuminuria and serum lipid (TC, TG, LDL-C) in both groups were improved, urinary albumin in treatment group was significantly decreased (P <0.05). The treatment group improved significantly better than the control group (P <0.05). Conclusion Danhong injection combined with lipoic acid injection treatment of early diabetic nephropathy significant effect, and the effect is better than single injection of lipoic acid.