目的了解浙江省台州市适龄儿童扩大国家免疫规划(national immunization program,NIP)疫苗接种现状。方法采用“分层整群随机抽样”方法,对台州市所辖9个县(市、区)随机抽取45个乡镇、90个村和9个流动人口聚集地,采用“入户见人查证”方法进行疫苗接种情况调查。结果本次共调查2202名儿童,其中本地儿童1922名,流动儿童280名。本地儿童22剂次NIP疫苗接种率,除A群C群脑膜炎球菌多糖疫苗(MPV-A+C2)外,其余疫苗接种率均>95%,含麻类疫苗首针(MCV1)及时接种率89.64%,乙型病毒性肝炎(乙肝)疫苗首针(Hep B1)及时接种率98.60%、五苗全程(BCG、OPV1-3、DTP1-3、Hep B1-3、MCV1)接种率96.63%。除(MPV-A+C1)、(MPV-A+C2)和OPV4外,本地儿童加强免疫疫苗接种率各年龄组之间差异有统计学意义(P<0.001);流动儿童除口服脊髓灰质炎减毒活疫苗(OPV)第4剂(OPV4)90.28%、A群C群脑膜炎球菌多糖疫苗第1剂(MPV-A+C1)89.44%、A群C群脑膜炎球菌多糖疫苗第2剂(MPV-A+C2)90.00%、甲型病毒性肝炎疫苗(Hep A)91.89%、白破(DT)疫苗94.12%外,22剂次NIP疫苗其余剂次接种率均>95%;含麻类疫苗首针(MCV1)及时接种率84.46%、乙肝疫苗首针(Hep B1)及时接种率91.79%、五苗全程(BCG、OPV1-3、DTP1-3、Hep B1-3、MCV1)接种率94.64%。流动儿童各年龄组加强免疫疫苗接种率差异无统计学意义(P>0.05)。结论台州本地儿童和流动儿童NIP疫苗接种率均处于较高水平,且A群C群脑膜炎球菌多糖疫苗和白破疫苗接种率较2013年明显提高。 Objective To understand the current situation of national immunization program (NIP) vaccination among school-age children in Taizhou, Zhejiang Province. Methods Using the “stratified cluster random sampling” method, we randomly selected 45 townships, 90 villages and 9 floating population sites in 9 counties (cities and districts) under the jurisdiction of Taizhou City. Person verification "method of vaccination investigation. Results A total of 2,202 children were surveyed, including 1922 local children and 280 floating children. The local vaccination rate of 22 doses of NIP for all children except the group A, group C meningococcal polysaccharide vaccine (MPV-A + C2), the other vaccination rates were> 95%, including the first dose of bovine vaccine (MCV1) timely vaccination rate 89.64%, Hep B1 was 98.60%, BCG, OPV1-3, DTP1-3, Hep B1-3 and MCV1 were 96.63%. In addition to (MPV-A + C1), (MPV-A + C2) and OPV4, the local vaccination rate of booster vaccination was statistically significant among all age groups (P <0.001). In addition to oral polio 90.28% of OPV4 (OPV4), 89.44% of group A meningococcal polysaccharide vaccine (MPV-A + C1), Group A, Group C meningococcal polysaccharide vaccine, second dose The vaccination rate of the remaining doses of 22 doses of NIP vaccine was> 95% except 90.00% of the total vaccine (MPV-A + C2), 91.89% of the Hepatitis A virus (Hep A) and 94.12% of the white vaccine The first vaccination of MCV1 was 84.46%, the timely vaccination rate of Hep B1 was 91.79%, the vaccination rate of BCG, OPV1-3, DTP1-3, Hep B1-3 and MCV1 94.64%. There was no significant difference in vaccination rate between floating children in all age groups (P> 0.05). Conclusion The vaccination rates of local children and migrant children in Taizhou are at a high level, and the immunization rates of meningococcal polysaccharide vaccine of Group A, Group C and white vaccination are obviously higher than those of 2013.