A gas-cooled nuclear reactor combined with a Brayton cycle shows promise as a technology for high-power space nuclear power systems.Generally,a helium-xenon gas mixture with a molecular weight of 14.5-40.0 g/mol is adopted as the working fluid to reduce the mass and volume of the turbomachinery.The Prandtl number for helium-xenon mixtures with this recommended mixing ratio may be as low as 0.2.As the convective heat transfer is closely related to the Prandtl number,different heat transfer correlations are often needed for fluids with various Prandtl numbers.Previous studies have established heat transfer correlations for fluids with medium-high Prandtl numbers(such as air and water)and extremely low-Prandtl fluids(such as liquid metals);however,these cor-relations cannot be directly recommended for such helium-xenon mixtures without verification.This study initially assessed the applicability of existing Nusselt number cor-relations,finding that the selected correlations are unsuit-able for helium-xenon mixtures.To establish a more general heat transfer correlation,a theoretical derivation was conducted using the turbulent boundary layer theory.Numerical simulations of turbulent heat transfer for helium-xenon mixtures were carried out using Ansys Fluent.Based on simulated results,the parameters in the derived heat transfer correlation are determined.It is found that calculations using the new correlation were in good agreement with the experimental data,verifying its appli-cability to the turbulent heat transfer for helium-xenon mixtures.The effect of variable gas properties on turbulent heat transfer was also analyzed,and a modified heat transfer correlation with the temperature ratio was estab-lished.Based on the working conditions adopted in this study,the numerical error of the property-variable heat transfer correlation was almost within 10％.