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３０例胃手术病人，随机分为全麻、硬膜外、全麻加硬膜外三组，每组１０例，对围术期血浆儿茶酚胺进行了观察。结果表明，在全麻组和硬膜外组麻醉后、术中及术后均有不同程度的血肾上腺素和去甲肾上腺素水平升高，与入室时相比差异显著（Ｐ＜０．０１）；而混合组虽有增高，但与入室时相比无明显差异（Ｐ＞０．０５）。多巴胺无论在组内还是在组间比较均无差异。作者认为单纯全麻和／或硬膜外麻醉均不能有效地抑制上腹部手术引起的应激反应，而两种方法并用却有效地抑制上腹部手术的应激反应。
Thirty patients with gastric surgery were randomly divided into three groups: general anesthesia, epidural, general anesthesia plus epidural, 10 patients in each group. Plasma catecholamines were observed during perioperative period. The results showed that in anesthesia group and epidural group after anesthesia, intraoperative and postoperative have varying degrees of blood adrenaline and norepinephrine levels, compared with the influx of significant differences (P <0.01 ), While the mixed group had no significant difference (P> 0.05) when compared with the infants when they entered the room. There was no difference in dopamine between groups or between groups. The authors believe that both general anesthesia and / or epidural anesthesia can not effectively inhibit the stress response caused by upper abdominal surgery, while the combination of the two methods is effective in inhibiting the stress response of upper abdominal surgery.