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目的清除标本内甲醛,消除强烈刺激性气味,降减其毒性。方法采用自制的碱性水溶性药物溶液对经甲醛防腐固定的标本进行浸泡或灌注处理后,抽取标本腔隙内液体作p H值检测和采用乙酰丙酮分光光度法检测标本甲醛含量。结果 1尸体腔隙内积液p H值由原来的3.8±0.2增加到6.0±0.2(P<0.05);甲醛浓度由16.7%±0.2%降到0.7%±0.1%(P<0.005)。2标本腔隙内积液p H值由原来的4.0±0.3增加到6.3±0.2(P<0.05);甲醛浓度由18.1%±0.2%降到0.5%±0.2%(P<0.005)。3尸体腔隙内积液甲醛浓度由原来的3.21 mg/m3降到0.08 mg/m3(P<0.005);标本腔隙内积液甲醛浓度由原来的3.54 mg/m3降到0.10 mg/m3(P<0.005)。结论碱性水溶性药物能显著清除尸体或标本内甲醛,降减甲醛毒性。
Objective To remove formaldehyde in samples, eliminate strong irritant odor and reduce its toxicity. Methods After self-made alkaline water-soluble drug solution was immersed in perfusate or perfusion treated with formaldehyde, the liquid in the sample cavity was extracted for determination of p H value and the content of formaldehyde in the sample was detected by acetylacetone spectrophotometry. Results The p value of effusion in the corpus cavity increased from 3.8 ± 0.2 to 6.0 ± 0.2 (P <0.05). The formaldehyde concentration decreased from 16.7% ± 0.2% to 0.7% ± 0.1% (P <0.005). The p value of effusion in the lacunar cavity increased from 4.0 ± 0.3 to 6.3 ± 0.2 (P <0.05). The concentration of formaldehyde decreased from 18.1% ± 0.2% to 0.5% ± 0.2% (P <0.005). (3) The concentration of effluent formaldehyde in the lacunar cavity decreased from 3.21 mg / m3 to 0.08 mg / m3 (P <0.005), the effluent formaldehyde concentration in the lacunar cavity decreased from 3.54 mg / m3 to 0.10 mg / m3 P <0.005). Conclusions Alkaline water-soluble drugs can significantly remove the formaldehyde in the body or specimen and reduce the toxicity of formaldehyde.