论文部分内容阅读
鉴于近几年来伤寒杆菌和痢疾杆菌耐药菌株日趋增加,用氯霉素治疗肠伤寒和菌痢疗效下降,复发率高。1974年我科应用呋喃唑酮治疗伤寒83例,收到满意疗效,但发现个别病例有溶血反应,不够理想。故1975年我科又试用国产磺胺-5-甲氧嘧啶(SMD)+抗菌增效剂甲氧苄胺嘧啶(TMP)治疗成人和儿童肠伤寒100例以及急性典型菌痢74例,取得较为满意疗效。本组同期用氯霉素治疗伤寒12例,以及氯霉素(或四环素)+呋喃唑酮治疗急性菌痢8例作对照观察,兹将其结果和有关问题分析和讨论如下:
In view of the increasing number of Salmonella typhi and Shigella dysenteriae resistant strains in recent years, the efficacy of chloramphenicol in the treatment of typhoid and bacillary dysentery is reduced and the recurrence rate is high. In 1974, our department applied furazolidone to treat 83 cases of typhoid fever and received satisfactory curative effect. However, hemolysis was found in some cases, which is not ideal. Therefore, in 1975, our department also tried domestic sulfa-5-methoxy-pyrimidine (SMD) + antibacterial synergist trimethoprim (TMP) treatment of intestinal typhoid fever in adults and children, 100 cases and 74 cases of acute typical bacillary dysentery, and achieved more satisfaction Efficacy. This group over the same period with chloramphenicol in the treatment of typhoid fever in 12 cases, and chloramphenicol (or tetracycline) + furazolidone treatment of acute bacillary dysentery in 8 cases as a control, we will analyze the results and related issues and discussed as follows: