恶性肿瘤发病率及死亡率在我国均很高,且就诊时大多已为晚期。因此加强肿瘤病因、病机及诊疗的研究,提高早期诊断率及疗效已成为临床工作的重点;而近年来大量研究表明血液中IGFs水平升高,与乳腺癌、肺癌、肝癌、胃癌、结肠癌等恶性肿瘤发病呈明显正相关,IGFs的信号通路研究有望 The incidence and mortality of malignant tumors in our country are very high, and most of the treatment has been late. Therefore, strengthening the study of etiopathogenisis, pathogenesis and diagnosis and treatment, and improving the early diagnosis rate and efficacy have become the focus of clinical work. In recent years, a large number of studies have shown that the levels of IGFs in the blood are elevated and are associated with breast cancer, lung cancer, liver cancer, gastric cancer, colon cancer And other malignant tumors showed a significant positive correlation, IGFs signaling pathway is expected