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近几年来,在美国、欧洲和一些发展中国家所进行的流行病学研究结果证实在感染了人类免疫缺陷病毒(HIV)患者中有部分病人同时重叠感染了人T淋巴细胞白血病病毒-Ⅰ(HTLV-Ⅰ)、HTLV-Ⅱ。HTLV-Ⅰ感染可引起T淋巴细胞白血病和神经系统并发症。HTLV-Ⅱ虽与HTLV-Ⅰ有60%基因组序列相同,但对其引起人类疾病的确切形式尚不十分清楚。引人注意的是,单纯感染HTLV-Ⅰ时,病人体内CD_4~+淋巴细胞计数增加,可能系T_H细胞增殖。探讨HIV和HTLV-Ⅰ重
In recent years, epidemiological studies carried out in the United States, Europe and some developing countries have confirmed that some patients infected with human immunodeficiency virus (HIV) are simultaneously infected with human T-lymphocyte leukemia virus- HTLV-Ⅰ), HTLV-Ⅱ. HTLV-I infection can cause T-cell leukemia and neurological complications. Although HTLV-II has the same 60% genomic sequence as HTLV-I, the precise form of HTLV-I causing human disease is not yet clear. Strikingly, when infected with HTLV-I alone, the number of CD_4 ~ + lymphocytes in the patient increased, possibly due to the proliferation of T_H cells. Explore HIV and HTLV-I weight