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临床应用当归历史悠久而广泛,药理研究也日渐深入。有关当归对血管方面的影响和对实验性心律失常的作用,我室已有报导。本实验又观察了当归(25％注射液,湖北医学院附属二医院制)对家兔实验性心肌梗塞的作用。实验用家兔17只,戊巴比妥钠静脉麻醉,经胸骨左缘开胸,不损伤两肺胸膜,在心尖与冠状沟之间结扎冠脉左室支,记录Ⅱ及胸前导联心电图。闭胸喂养24小时后麻醉开胸取心,将左室横切成薄片,用硝基四氮唑兰(NBT)溶液染色。计算心肌梗塞范围。
The clinical application of Angelica has a long history and a wide range of pharmacological research is also deepening. The effects of Angelica on vascular and the effect on experimental arrhythmia have been reported in our department. This experiment also observed the effect of Angelica sinensis (25% injection, manufactured by the Second Affiliated Hospital of Hubei Medical College) on experimental myocardial infarction in rabbits. Seventeen experimental rabbits were used. Pentobarbital sodium was used for intravenous anesthesia. The thorax was opened on the left edge of the sternum without damaging both lung pleura. The coronary left ventricular branch was ligated between the apex of the heart and the coronary sulcus. The recording II and chest lead electrocardiogram were recorded. . After 24 hours of closed-chest feeding, the chest was anesthetized, the left ventricle was transected into thin slices and stained with nitrotetrazolium blue (NBT) solution. Calculate the range of myocardial infarction.