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Talwar等提出睾丸内输精管注射BCG(Bacille Calmette Guerin)可做为男性避孕的免疫方法之一。其原理为免疫细胞突破血睾屏障进入输精管及生精管,这些免疫细胞引起免疫反应,对抗生精细胞的减数分裂,并使生精细胞成为对体内其它细胞而言的免疫异己细胞。Talwar等报告此方法在哺乳动物如人、猴、猿等有效,且无副作用,此方法主要
Talwar and coworkers have suggested that intragastric injection of BCG (Bacille Calmette Guerin) can be used as a method of immunization for male contraception. The principle is that immune cells break through the blood-testis barrier into the vas deferens and vas deferens, and these immune cells elicit an immune response that counters the meiosis of spermatogenic cells and makes spermatogenic cells immune-immune cells to other cells in the body. Talwar et al. Report that this method is effective in mammals such as humans, monkeys, apes and the like, and has no side effects, and this method is mainly