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目的:探讨原发性肝癌病位、病性与客观指标之间的相关性。方法:应用临床流行病学研究方法,收集617例原发性肝癌病例,采用关联规则分析方法,探析肝癌病位、病性与客观指标的相关性。结果:总胆红素、谷丙转氨酶、碱性磷酸酶、CA125、CA199、甲胎蛋白等指标升高与病位“胆”密切相关;谷草转氨酶、总胆红素、碱性磷酸酶、CEA、γ-谷氨酰转肽酶、谷丙转氨酶、CA125等指标升高与病位“脾”密切相关;碱性磷酸酶、谷丙转氨酶、CA125指标升高与病位“脾”“胆”均相关;CA125、CA199指标升高与病性“痰”密切相关;CA125、总胆红素指标升高与病性“湿”密切相关;CEA升高与病性“水停”密切相关;总胆红素升高与病性“热”密切相关;CA125升高与病性“阴虚”密切相关。结论:原发性肝癌病位、病性与某些客观指标之间存在一定的相关性。
Objective: To explore the correlation between the primary liver cancer location, pathology and objective indicators. Methods: A total of 617 cases of primary liver cancer were collected using clinical epidemiological methods. The association rules were used to analyze the correlation between the location and the pathological features of liver cancer and the objective indexes. Results: The elevated levels of total bilirubin, alanine aminotransferase, alkaline phosphatase, CA125, CA199 and alpha-fetoprotein were closely related to the “bitch” , CEA, γ-glutamyl transpeptidase, alanine aminotransferase, CA125 and other indicators of increased disease and “spleen” is closely related to alkaline phosphatase, alanine aminotransferase, CA125 index increased with the disease “ Spleen and gallbladder were closely related to CA125 and CA199, while CA125 and CA199 were closely related to pathogenic and sputum. High and pathogenic ”water stop “ is closely related to; elevated total bilirubin and disease ”hot “ is closely related; CA125 increased and disease ”Yin " is closely related. Conclusion: There is a certain correlation between the location and pathological features of primary liver cancer and some objective indicators.