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目的探讨血尿酸水平与急性脑梗死发病及预后的关系。方法检测129例急性脑梗死患者与120例健康组的血尿酸水平及相关指标进行比较,分析其相关性。结果急性脑梗死患者血尿酸水平及异常率明显增高,与对照组之间差异存在非常显著性(P<0.01),在急性脑梗死患者中,血尿酸异常组高血压、高血糖、高血脂及高纤维蛋白原血症的发生率比正常组明显增高,血尿酸异常组较正常组入院第21天神经功能缺损的程度差异存在非常显著性(P<0.01)。结论血尿酸水平与急性脑梗死的发病密切相关,是预后不良的预测因素。
Objective To investigate the relationship between serum uric acid level and the incidence and prognosis of acute cerebral infarction. Methods The levels of serum uric acid in 129 patients with acute cerebral infarction and 120 healthy controls were measured and their correlations were analyzed. Results Serum uric acid level and abnormal rate in patients with acute cerebral infarction were significantly higher than those in control group (P <0.01). In patients with acute cerebral infarction, the levels of blood pressure, hyperglycemia, hyperlipidemia, The incidence of hyperfibrinogenemia was significantly higher than that of the normal group. There was a significant difference in the degree of neurological deficits between the normal group and the normal group (P <0.01). Conclusion Serum uric acid level is closely related to the onset of acute cerebral infarction and is a predictor of poor prognosis.