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本文回顾了美国克利夫兰大学医院等在1982年底以前10年间101例声门鳞癌的治疗。计Ⅰ期患者38例,其中28例接受放疗(6600rad),有1例复发再予全喉切除;3及5年生存率分别为92％及85％;另10例作手术治疗。Ⅱ期患者14例,其中放疗8例,全喉切除6例,3及5年生存率均为91％。Ⅲ期患者31例,其中13例全程放疗,18例全喉切除,3及5年生存率为91％及63％。Ⅳ期患者18例,其中2例全程放疗,16例全喉切除,3及5年生存率为69％及52％。对Ⅱ～Ⅳ期部分患者应兼作根治性颈淋巴廓清或术前放疗,对Ⅲ～Ⅳ期患者应以手术治疗为主,部分患者还须作术后放疗。对Ⅳ期未触及颈转移淋巴结患者各4例,分别采用同侧预防性颈淋巴廓清及术后放疗,前者生存率略高于后者
This article reviews the treatment of 101 cases of glottic squamous cell carcinoma in the 10 years before the end of 1982 in Cleveland University Hospital. Of the 38 patients with stage I, 28 received radiation therapy (6600 rad), 1 had recurrent recurrent laryngectomy, 3 and 5 year survival rates were 92% and 85%, respectively. The other 10 patients were treated with surgery. There were 14 patients with stage II disease, including 8 cases of radiotherapy and 6 cases of total laryngectomy. The 3 and 5 year survival rates were 91%. There were 31 patients with stage III disease, including 13 cases of total radiotherapy and 18 cases of total laryngectomy. The 3 and 5 year survival rates were 91% and 63%. Eighteen patients were in stage IV, of whom 2 were treated with full radiotherapy and 16 were treated with total laryngectomy. The 3- and 5-year survival rates were 69% and 52%. Part II ~ IV patients should be combined with radical cervical lymph node dissection or preoperative radiotherapy, patients with stage III ~ IV surgery should be the main, some patients must also be postoperative radiotherapy. Four patients with unmetastatic cervical lymph node metastases in stage IV were treated with ipsilateral prophylactic cervical lymph node dissection and postoperative radiotherapy. The survival rate of the former was slightly higher than that of the latter.