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观察不同时点螺旋藻对染尘肺泡巨噬细胞的保护功能.方法采用肺泡巨噬细胞体外培养方法.结果随培养时间延长,各组LDH、MDA含量均明显升高,SOD含量均明显下降,尤其在12小时前变化较明显,但经SP处理的两组则有明显的拮抗作用;表现在:各孵育时点SIO2组LDH、MDA含量最高,SOD最低,其次分别为SIO2+SP、生理盐水组、SP组,各组LDH、MDA、SOD含量经统计学处理均有显著性差异(P＜0?01).结论(1)SP具有提高染尘PAM体外抗氧化水平和保护PAM、增强PAM吞噬功能作用.(2)SP提高PAM体外抗氧化水平作用可能与其含有丰富营养成分有关.“,”Objective To study the protective effects of spirulina on pulmonary alveolar macrophage exposed to quartz dust at different time.Methods Alveolar macrophage was cultured in vitro and its levels of LDH MDA and SOD were determined.Results Levels of LDH and MDA in the alveolar macrophage elevated and level of SOD reduced significantly with the duration of culture,especially before 12 hours for culture.But,treatment with spirulina had obviously an...