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目的 探讨去甲肾上腺素用法不同，对消化性溃疡急性出血的止血效果。方法 将消化性溃疡急性出血64例随机分为治疗组与对照组。治疗组：去甲肾上腺素8 mg溶于生理盐水100 ml中口服或胃管内注入，每15 min 1次，连续4次，然后每1 h给药1次，连续3次，再后每4 h 1次;对照组：去甲肾上腺素8 mg溶于生理水中口服或胃管内注入，每6 h给药1次。两组均通过检测血压、脉搏、大便潜血、血红蛋白来观察止血效果。结果 治疗组平均出血时间2.4 d，对照组平均止血时间3.8 d，两组止血时间比较差异显著(P<0.01)。结论 消化性溃疡急性出血采用去甲肾上腺素盐水口服或胃管内注入进行止血，其缩短给药时间的效果明显优于常规给药方法。
Objective To investigate the effect of norepinephrine on hemostasis of peptic ulcer acute hemorrhage. Methods 64 cases of peptic ulcer acute hemorrhage were randomly divided into treatment group and control group. Treatment group: norepinephrine 8 mg dissolved in saline 100 ml oral or gastric tube injection, once every 15 min, 4 times in a row, and then every 1 h dosing for 3 times, and then every 4 h 1 times; control group: norepinephrine 8 mg dissolved in physiological water, orally or intragastrically injected, administered once every 6 h. Both groups through the detection of blood pressure, pulse, fecal occult blood, hemoglobin to observe the effect of hemostasis. Results The average bleeding time was 2.4 days in the treatment group and 3.8 days in the control group. There was significant difference between the two groups in the bleeding time (P <0.01). Conclusions Acute peptic ulcer hemorrhage is achieved by oral administration of norepinephrine saline or gastric tube instillation. The shortened administration time is obviously better than the conventional administration method.