本文报告用２０％甘露醇治疗脑血栓形成４２例，并以低分子右旋醣酐（低右）治疗的３６例作为对照组。结果治疗组显效率７１．４％，总有效率９０．４％，对照组显效率４４．４％，总有效率６３．８％。两组比较，差异显著（Ｐ＜０．００１），说明２０％甘露醇对脑血栓形成具有良好的治疗作用。文中并就２０％甘露醇对脑血栓形成的作用机理进行了讨论。 This article reports the treatment of cerebral thrombosis with 20% mannitol in 42 cases, and low molecular dextran (low right) treatment of 36 cases as a control group. Results In the treatment group, the effective rate was 71.4%, the total effective rate was 90.4%, the effective rate in the control group was 44.4% and the total effective rate was 63.8%. The differences between the two groups were significant (P <0.001), indicating that 20% mannitol has a good therapeutic effect on cerebral thrombosis. The mechanism of action of 20% mannitol on cerebral thrombosis is discussed in the paper.