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目的：了解速克喘干粉吸入剂在慢性阻塞性肺疾病（ＣＯＰＤ）急性发作期的作用。方法：ＣＯＰＤ急性发作期３０例（男性２１例，女性９例，年龄６９±ｓ６ａ），用速克喘吸入４００μｇ。结果：临床总有效率为７５％，吸入后５ｍｉｎ肺功能即有明显改善，２ｈ后用力肺活量，１ｓ用力呼气量和最大呼气流速有明显增加（Ｐ＜０．０５，Ｐ＜０．０１），有效时间达４ｈ以上。无明显不良反应。结论：ＣＯＰＤ急性发作期病人用速克喘可缓解胸闷、气急等症状。
OBJECTIVE: To investigate the effect of dry grams dry powder inhaler in acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods: 30 cases of acute exacerbation of COPD (21 males and 9 females, age 69 ± s6a) were challenged with glipizide 400 μg. Results: The total clinical effective rate was 75%. Pulmonary function was significantly improved 5min after inhalation. After 2h, forced vital capacity, forced expiratory volume at 1 second and maximum expiratory flow rate increased obviously (P <0.05, P <0.01) ), The effective time of 4h or more. No obvious adverse reactions. Conclusion: Patients with acute exacerbation of COPD can relieve chest tightness, shortness of breath and other symptoms with fast gram-asthma.