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目的探讨甲硝唑与克霉唑联合治疗复发性阴道炎的临床效果。方法选取2015年5月至2016年5月深圳市龙岗区中医院收治的112例复发性阴道炎患者作为研究对象,根据治疗方案分为仅采用甲硝唑治疗的对照组(56例)与采用甲硝唑联合克霉唑治疗的观察组(56例),比较两组不同类型复发性阴道炎的临床效果、总治疗效果、治疗后3个月复发情况、临床症状改善情况及症状消失时间、不良反应发生情况。结果采用甲硝唑联合克霉唑治疗的观察组患者显效率、总有效率均显著高于对照组,复发率明显低于对照组,且不同类型复发性阴道炎治疗的总有效率也均显著高于对照组,差异均有统计学意义(均P<0.05);观察组临床症状改善患者比例以及消失时间均显著优于对照组,差异均有统计学意义(均P<0.05)。结论甲硝唑联合克霉唑对于各类型复发性阴道炎均具有理想的治疗效果,可有效改善患者临床症状,缩短恢复时间,减少复发率。
Objective To investigate the clinical effect of metronidazole combined with clotrimazole in the treatment of recurrent vaginitis. Methods From May 2015 to May 2016, 112 patients with recurrent vaginitis admitted to Longgang District Chinese Medicine Hospital were enrolled. According to the treatment plan, the patients in control group (56 cases) treated with metronidazole only The observation group (56 cases) treated with metronidazole combined with clotrimazole compared the clinical effects, the total curative effect, the recurrence 3 months after treatment, the improvement of clinical symptoms and the disappearance of symptoms in two groups of different types of recurrent vaginitis, Adverse reactions occurred. Results The effective rate and total effective rate of the observation group treated with metronidazole combined with clotrimazole were significantly higher than those of the control group, the recurrence rate was significantly lower than that of the control group, and the total effective rate of the treatment of different types of recurrent vaginitis was also significant (All P <0.05). The proportion of patients with clinical symptom improvement in the observation group and the disappearance time were significantly better than those in the control group (all P <0.05). Conclusion Metronidazole combined with clotrimazole for all types of recurrent vaginitis have an ideal therapeutic effect, which can effectively improve the clinical symptoms, shorten the recovery time and reduce the recurrence rate.