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目的研究滁州市C群流脑的流行特征与控制措施,为今后C群流脑防控工作提供科学依据。方法对2004~2005年度流脑个案调查、实验室检测结果进行分析。结果28例流脑患者中检出5例C群Nm,病例的密切接触者中检出4株C群Nm;在地区分布中,南谯区乌衣镇中学发生5例C群流脑为局部爆发,其余为散发病例;病倒中学生占71.42%,10~20岁年龄组占71.42%;有A群流脑疫苗免疫史占82.14%,有5例流脑A+C二价疫苗免疫失败。结论C群流脑病例来势凶猛,病程进展快,病死率高;接种A群流脑疫苗不能阻止C群流脑流行;为防止发病控制疫情扩散,应对20岁以下人群和在校的大、中专学生等易感群体提供免疫保护。
Objective To study the epidemiological characteristics and control measures of meningococcal brain in Group C of Chuzhou and provide a scientific basis for prevention and control of Group C meningitis in the future. Methods The meningococcal case investigation and laboratory test results from 2004 to 2005 were analyzed. Results In 28 cases of meningitis patients, 5 cases of C group Nm were detected, and 4 cases of C group Nm were detected in the close contacts of cases. In the distribution, 5 cases of C group meningitis occurred in Wuyi middle school in Nanxun district Outbreaks, and the rest were sporadic cases; 71.42% of them were sick and 70.42% of them were in the age group of 10-20 years old; 82.14% of the patients were immunized with group A meningitis vaccine and 5 cases of immunosuppression with the binary vaccine of meningococcal A + C vaccine. Conclusions The meningitis cases in Group C are ferocious with fast progression and high mortality rate. Inoculation of Group A meningitis vaccine can not prevent the epidemic of Group C meningitis. In order to prevent the onset of disease control and spread of the epidemic, Students and other vulnerable groups to provide immunological protection.