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目的:就呼吸内科抗菌药物继发真菌感染76例进行分析。方法:选取2013年1月-2014年1月我院呼吸内科所收治的76例下呼吸道感染患者,对其进行分析探讨。结果:抗菌药物应用次数最多的为三代头孢菌素(头孢他啶、舒巴坦+头孢哌酮),其次为喹诺酮类(左氧氟沙星)、氨基糖甘类(硫酸阿米卡星)。本组患者中有8例(10.53%)单用抗菌药物(头孢他啶、舒巴坦+头孢哌酮),44例(57.89%)联用3种抗菌药物(硫酸阿米卡星+左氧氟沙星+三代头孢),24例(31.58%)联用2种抗菌药物(左氧氟沙星+三代头孢)。结论:应该对用药指征进行严格掌握,抗菌药物要应用合理,为了有效地控制患者的病情,还可以给予大剂量的抗菌药物,待患者病情有所缓解之后,给药间隔时间可以适当地调整或者减量,广谱抗菌药物能单用不联用。
Objective: To analyze 76 cases of secondary fungal infections in respiratory medicine. Methods: A total of 76 patients with lower respiratory tract infection admitted to our hospital from January 2013 to January 2014 were selected and analyzed. Results: The third generation cephalosporins (ceftazidime, sulbactam + cefoperazone) were the most frequently used antibiotics, followed by quinolones (levofloxacin) and aminosugar (amikacin sulfate). Eight patients (10.53%) were treated with antibacterial drugs (ceftazidime, sulbactam + cefoperazone) and 44 (57.89%) patients with three antibacterials (amikacin sulfate + levofloxacin + third generation cephalosporin ), 24 cases (31.58%) combined with two kinds of antibacterial drugs (levofloxacin + third generation cephalosporins). Conclusion: The indications should be strictly controlled. The antimicrobial agents should be applied reasonably. In order to effectively control the patient’s condition, high doses of antimicrobial agents can be given. After the patient’s condition has been alleviated, the dosing interval can be appropriately adjusted Or reduction, broad-spectrum anti-bacterial drugs can not be used alone.