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目的：研究克拉玛依地区皮肤利什曼病的临床类型及病理。方法：分析整理１９８８—１９９４年确诊的９０例皮肤利什曼病的临床及病理资料。结果：该病主要临床类型可分为丘疹、斑块、溃疡性结节和结节性痒疹型４种。丘疹及斑块型主要由利什曼原虫引起的巨噬细胞聚集和炎症反应；溃疡性结节型是皮肤组织坏死、液化及脱落，溃疡边缘的真皮层呈充血和水肿，并有中性粒细胞和淋巴细胞浸润，在浸润区内可查见原虫；结节性痒疹型主要是真皮层形成结核样结节，利什曼原虫很少。患者的血象正常，Ｂ超检查脾脏的大小与当地正常人无明显差异。结论：克拉玛依地区皮肤利什曼病有丘疹、斑块、溃疡性结节及结节性痒疹型４种临床类型，且各有病理特征。
Objective: To study the clinical type and pathology of cutaneous leishmaniasis in Karamay area. Methods: The clinical and pathological data of 90 cases of cutaneous leishmaniasis diagnosed from 1988 to 1994 were analyzed. Results: The main clinical types of the disease can be divided into papules, plaques, ulcerative nodules and nodular prurigo 4. Papules and plaques are mainly caused by Leishmania macrophage aggregation and inflammation; ulcerated nodules are skin tissue necrosis, liquefaction and loss, the dermis of the ulcer edge of congestion and edema, and neutrophils And lymphocyte infiltration in the infiltration zone can be found protozoa; prurigo nodular dermis is mainly the formation of tuberculosis-like nodules, Leishmania few. Patients with normal blood, B-ultrasound examination of the size of the spleen and the local no significant difference. Conclusion: There are four clinical types of cutaneous leishmaniasis in the Karamay region, including papules, plaques, ulcerated nodules and prurigo nodularis, each with pathological features.