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Objective In this study,a primary culture system for the rat distal pulmonary arterial smooth muscle cell(PASMC)was established to observe the effect of Bortezomib treatment on the basal intracellular calcium concentration([Ca2+]i),store operated calcium entry(SOCE)and Orai-1 expression in rat PASMC.Methods
Objective In this study, a primary culture system for the rat distal pulmonary arterial smooth muscle cell (PASMC) was established to observe the effect of Bortezomib treatment on the basal intracellular calcium concentration ([Ca 2+] i), store operated calcium entry (SOCE) and Orai-1 expression in rat PASMC. Methods