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背景 最近的几次调查研究了处于高度危险状态供血者克鲁斯锥虫血清流行率,但很少有关于低危供血者的资料。本项研究的目的是评估克鲁斯锥虫病在低感染的供血人群中的血清流行率。研究设计与方祛在为期10个月的期限内,对所有美国西南部红十字会的同种供血者的血样作酶免法检测克鲁斯锥虫抗体。结果通过放射免疫沉淀法确证。为向确证血清阳性供血者提供医疗建议,并对重复献血者开始作回顾性调查。结果 总共有100089次捐血作了测验。150例有重复反应,3例(0.003％)克鲁斯锥虫抗体确证为阳性。这3名血清阳性供血者都来自德克萨斯的Waw地区,估计该区
Background Several recent surveys have investigated the prevalence of serums of Trypanosoma cruzi in highly dangerous blood donors, but few data are available on low-risk donors. The purpose of this study was to assess the seroprevalence of cruzi trypanosomiasis in a low-infection donor population. Study Design and Disinfection During the 10-month period, the blood samples from all blood donors of the Red Cross Society of the Southwestern United States were tested for enzyme-labeled Trypanosoma cruzi antibodies. The results were confirmed by radioimmunoprecipitation. To provide medical advice to confirmed seropositive donors and to begin a retrospective survey of repeat donors. A total of 18,089 blood donations were tested. 150 cases had repeated reactions, and 3 cases (0.003%) of Trypanosoma cruzi antibodies were confirmed as positive. The three seropositive blood donors came from the Waw area in Texas, estimating the area