对电压敏感的钠离子通道在正常的生理过程中一般不与神经递质或生理配基相结合。但是,它却是一些神经毒素和药物作用的分子靶。因此,该离子通道又称为神经毒素受体,计分三种受点,分别与以下三类毒素配基具有亲和力;1.河豚毒(Tetrodotoxin)与石房蛤毒(Saxitoxin)。2.南美蟾毒(Eafrachotoxin)、乌头碱(Aconitine)、藜芦碱(Ver-atridine)和灰安毒(Grayanotoxin)。3.北非蝎毒(Scorpioa Toxin)和海葵毒 Voltage-sensitive sodium channels are not normally associated with neurotransmitters or physiological ligands during normal physiologic processes. However, it is a molecular target of some neurotoxins and drugs. Therefore, the ion channel, also known as the neurotoxin receptor, scored three receptors, respectively, with the following three types of toxin ligand affinity; 1. Tetrodotoxin (Tetrodotoxin) and Saxitoxin (Saxitoxin). 2. Eafrachotoxin, Aconitine, Ver-atridine and Grayanotoxin. 3. North African scorpion poison (Scorpioa Toxin) and anemone poison