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采用１：１配比，通过病例一对照调查方法，对湖北省麻城地区６３对３～６岁儿童进行了智力低下影响因素的调查。经过单因素及条件Ｌｏｇｉｓｔｉｃ回归分析，结果表明：影响儿童智力低下的遗传生物学因素有父母近亲婚配、母亲妊娠中毒症、母亲妊娠生活事件、母亲吸烟、死胎死产史等；家庭因素有母亲文化程度、父亲职业、家庭经济收入等。以上述影响因素作判别指标，依据极大似然判别原理，对两组资料分别做了判别分类，经检验判别结果均有高度显著性。
A 1: 1 ratio was used to investigate the influencing factors of mental retardation in 63 pairs of children aged 3-6 years in Macheng, Hubei Province. After univariate and conditional Logistic regression analysis, the results showed that: the genetic biological factors affecting children with mental retardation include the marriage of parents and their cousins, the pregnancy of pregnant women, the pregnancy of pregnant women, the smoking of mothers and the stillbirth of stillbirth. The family factors include mother’s culture Degree, father’s occupation, family income and so on. According to the principle of maximum likelihood determination, the two groups of data are respectively classified and classified according to the above-mentioned influencing factors. The results of the test are highly significant.