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70年代初提出对血管紧张素Ⅱ（AⅡ）受体部位的拮抗作用，可以作为抑制AⅡ作用的ACE抑制作用的一种可供选择的方法。这种新途径能够为高血压和心衰提供更好的治疗，因为AⅡ除了ACE以外还可以由其他的酶产生。AⅡ受体已鉴别出两个亚型，即AT1和AT。。目前已知G蛋白偶联的AT；受?
In the early 1970s, the proposed antagonism of angiotensin Ⅱ (AⅡ) receptor site could be used as an alternative method to inhibit the ACE inhibitory effect of AⅡ. This new route offers better treatment of high blood pressure and heart failure because AII can be produced by other enzymes in addition to ACE. AII receptors have identified two subtypes, AT1 and AT. . Currently known G protein-coupled AT; by?