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D-S是一强力的葡萄糖-6磷酸盐脱氢酶抑制剂,正常存于人体血浆,其浓度在青春期时达高峰,随年龄的增长而渐下降。已知D-S可抑制人体皮肤、肺、结肠和乳腺组织等肿瘤的生长。作者进一步研究D-S对体内外胰腺癌细胞生长的作用。在体外,选用胰腺癌细胞系MiaPaCa-2、Capan-1
D-S is a potent glucose-6-phosphate dehydrogenase inhibitor that is normally present in human plasma. Its concentration peaks during puberty and gradually declines with age. D-S is known to inhibit the growth of tumors such as human skin, lungs, colon, and breast tissue. The authors further studied the effect of D-S on the growth of pancreatic cancer cells in vitro and in vivo. In vitro, the pancreatic cancer cell line MiaPaCa-2, Capan-1 was selected.