2004-2013年广州市户籍人口宫颈癌与宫体癌死亡趋势分析与比较

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目的分析与比较广州市2004-2013年户籍人口宫颈癌和宫体癌的死亡情况及变化趋势,为两种癌症的防治策略提供数据支持。方法收集2004-2013年广州市两种癌症全市发病和中心城市6区的死亡及户籍人口资料,计算粗发病和死亡率及世界人口标化率(世标率)。利用Jointpoint Regression Program软件统计时间变化趋势。结果2004-2013年广州市宫颈癌和宫体癌的年平均发病世标率分别为9.76/10万和8.54/10万;死亡世标率分别为1.76/10万和0.95/10万;发病年龄中位数分别为47岁和52岁。死亡率宫颈癌从30~岁组逐渐上升,宫体癌从40~岁组持续上升;10年来宫颈癌和宫体癌发病均呈上升趋势,年度变化百分比(average annual percent change,APC)分别为2.97%(Z=3.134,95%CI:0.8%~5.2%)和2.03%(Z=1.804,95%CI:-0.6%~4.8%);同期宫颈癌和宫体癌死亡也呈上升趋势,APC分别为3.35%(Z=1.323,95%CI:-2.4%~9.4%)和14.33%(Z=4.626,95%CI:6.9%~22.2%),增长幅度分别为29.49%和216.28%。结论广州市近10年来,虽然宫颈癌死亡率高于宫体癌,但宫体癌的死亡率上升迅速,增长速度明显高于宫颈癌。故在开展宫颈癌筛查项目的同时,重视宫体癌的防治,加强宫体癌预防措施的宣教。 Objective To analyze and compare the deaths and changes of cervical cancer and uterine cancer in census register population from 2004 to 2013 in Guangzhou City and provide data support for the prevention and treatment strategies for both cancers. Methods The data of death and census register population of two kinds of cancer in Guangzhou city and urban area from 2004 to 2013 in Guangzhou were collected to calculate the prevalence of fatal disease and mortality and the world population standardization rate. Using Jointpoint Regression Program software to measure the trend of time. Results The annual average rates of cervical cancer and uterine cancer in Guangzhou from 2004 to 2013 were 9.76 / lakh and 8.54 / lakh respectively. The death rates were 1.76 / lakh and 0.95 / lakh, respectively. The age of onset The median was 47 and 52 respectively. The incidence of cervical cancer increased gradually from 30 to 30 years old. The incidence of cervical cancer increased from 40 to 40 years old. The incidence of cervical cancer and uterine body cancer ten years increased. The average annual percent change (APC) 2.97% (Z = 3.134,95% CI: 0.8% -5.2%) and 2.03% (Z = 1.804,95% CI: -0.6% -4.8%). The death rates of cervical cancer and uterine cancer also increased during the same period, APC were 3.35% (Z = 1.323, 95% CI: -2.4% ~ 9.4%) and 14.33% (Z = 4.626,95% CI: 6.9% ~ 22.2%) with the growth rates of 29.49% and 216.28% respectively. Conclusions Although the death rate of cervical cancer is higher than that of uterine cancer in Guangzhou in the past 10 years, the mortality of uterine cancer has risen rapidly and the growth rate is obviously higher than that of cervical cancer. Therefore, in carrying out cervical cancer screening project at the same time, pay attention to the prevention and treatment of uterine cancer, to strengthen the prevention and treatment of uterine cancer education.
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