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应用单细胞微量凝胶电泳测试技术（microgelsinglecellelectrophoresisassay，MGE）检测氯乙烯对哺乳动物肝脏细胞（肝实质性细胞和非实质性细胞）DNA损伤情况。结果发现：氯乙烯可致肝实质性细胞DNA损伤，呈剂量-效应关系，对肝非实质性细胞只有在与肝实质性细胞混合培养时才出现一定程度的DNA损伤。本文就肝实质性细胞和非实质性细胞对氯乙烯敏感性差异的原因作了讨论。结果还表明，单细胞微量凝胶电泳技术是一项灵敏的测试动物细胞DNA损伤的方法。
The DNA damage of mammalian liver cells (hepatic parenchymal cells and non-parenchymal cells) was examined by microgelsinglecellelectrophoresisassay (MGE). The results showed that: Vinyl chloride can cause DNA damage in liver parenchymal cells in a dose-response relationship. Only a certain degree of DNA damage was observed in non-parenchymal cells only when mixed with hepatic parenchymal cells. This article discusses the reasons for differences in the sensitivity of hepatic parenchymal cells and non-parenchymal cells to vinyl chloride. The results also show that single-cell microgel electrophoresis is a sensitive method of testing DNA damage in animal cells.