论文部分内容阅读
合霉素、氯霉素味极苦,一般小儿很难服用。最近我们根据文献报导,试制了滴丸,用于临床效果很好,解决了小儿服药困难问题。(此外还用滴丸法制备了黄连素用以治疗小儿痢疾,收效亦好。)根据文献介绍,滴丸法是一种熔点较低的脂肪性的基质或水溶性的基质,将主药溶解或混悬后,滴入一种不相混合的液体冷却剂中,由于熔融物表面张力关系,即形成小球形的丸。我们根据其原理进行试制,今介绍如下。一、装置:与文献上介绍的一样,不过简化了很多。用一根内径3.5厘米,长85厘米的玻璃管,用一橡皮塞连在三角烧瓶上,内盛冷却剂——液体石腊,滴丸时系用药房内用的鱼肝由精滴管,其滴口外径为2.9毫米。二、处方:
Combinomycin, chloramphenicol extremely bitter, very difficult to take in children. Recently we reported based on the literature, trial-made drop pills for clinical effect is very good, to solve the problem of pediatric medication difficulties. (In addition, berberine is also prepared by the dropping pills method to treat pediatric diarrhea, and the effect is also good.) According to the literature, the dropping pills method is a kind of fatty matrix with low melting point or water-soluble matrix, Or suspended, dripped into an immiscible liquid coolant, forming pellets of pellets due to the surface tension of the melt. According to the principle of trial, we introduce the following. First, the device: the same as described in the literature, but simplified a lot. With a diameter of 3.5 cm, 85 cm long glass tube, with a rubber stopper attached to the conical flask, filled with coolant - liquid paraffin, drop pills when the Department of pharmacy with the fish liver by the fine dropper, The drop diameter of 2.9 mm. Second, the prescription: