目前测定某种物质引起肺纤维化的程度的方法,是使动物在吸尘室吸入某种粉尘,或向实验动物的气管内注入某种粉尘,经过6～12个月后,检测肺的生物化学或组织学变化。虽然此方法比较符合病理生理学,但有一大缺点,即:在应用近代方法最后肯定动物肺组织已发生明显的纤维化之前,实验动 The current method of determining the extent to which a substance causes pulmonary fibrosis is to allow the animal to inhale some kind of dust in the suction chamber or to inject some kind of dust into the trachea of ​​experimental animals. After 6 to 12 months, lung organisms Chemical or histological changes. Although this method is more in line with the pathophysiology, but there is a big flaw, namely: in the application of modern methods finally animal lung tissue has obvious fibrosis, the experimental move