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目的探讨红细胞平均体积(MCV)和红细胞体积分布宽度(RDW)在轻型地中海贫血和缺铁性贫血的鉴别意义。方法回顾性分析148例轻型地中海贫血和缺铁性贫血及50例正常已婚夫妇的MCV和RDW。结果①MCV在正常对照组明显高于缺铁性贫血组及轻型地中海贫血组(P<0.01),缺铁性贫血组RDW明显升高,与正常对照组和轻型地中海贫血组比较差异有显著性(P<0.01);②缺铁性贫血组以MCV下降RDW增高为主,比率为90.57%,标准型地中海贫血、β地中海贫血和α、β混合型地贫以MCV下降RDW正常为主,比率分别为84.31%、73.91%、68.75%,静止型地贫RDW均正常。结论临床上检测MCV及RDW有助于鉴别诊断轻型地中海贫血和缺铁性贫血。
Objective To investigate the differential significance of mean corpuscular volume (MCV) and erythrocyte bulk density (RDW) in thalassemia and iron deficiency anemia. Methods Retrospective analysis of 148 cases of mild thalassemia and iron deficiency anemia and 50 cases of normal married couples MCV and RDW. Results ①MCV was significantly higher in the control group than in the group of iron deficiency anemia and thalassemia minor (P <0.01), RDW in the group of iron deficiency anemia was significantly higher than that in the control group and the thalassemia group P <0.01). ② In the iron-deficiency anemia group, the MCV decreased RDW increased, the ratio was 90.57%. The prevalence of MCV decreased in normal thalassemia, β-thalassemia and α, 84.31%, 73.91% and 68.75% respectively. RDW in resting thalassemia were all normal. Conclusion The clinical detection of MCV and RDW is helpful for the differential diagnosis of thalassemia and iron deficiency anemia.