Microfluidics is a promising system for the manipulation of micro-nano particles and fluids.In this platform,alternating current(AC)electric field is usual an effective tool for the general particles control.However,traditional work paid more attention on the regular spherical particles with no obvious distinction when rotating,resulting in imprecise rotation speed calculation.In essence,non-spherical especially biocompatible particles are not only important for biology application but also significant for obtaining accurate rotating results.Hence,in this paper,SU-8,one of the most biocompatible materials was selected as the manipulation object.AC electric field is employed to rotate SU-8 microrods,in order to obtain a controllable rotation angle for both the accurate experimental results and biosensor applications.Firstly,Clausius-Mossotti(CM)factors frequency spectra with different surface conductance and medium conductivities are presented,thereby the theoretical formula is carried out,including both the torque and rotation velocity expressions of SU-8 microrods.Moreover,simulations for the electric field distribution are developed,indicating the rotating direction.Secondly,the quadrupole electrodes are used to generate rotating electric field,and the electrorotation of SU-8 microrods in different medium is carried out,showing that the particles rotate in the opposite direction of the electric field,meanwhile,the peak frequency increases with the conductivity increases.Finally,the experimental results are discussed and compared with theoretical analysis,and the comparison result shows that they have a good agreement.This work proposes an effective and controllable method to rotate microrods,showing extend application potentials in microelectronics and biosensors. Microfluidics is a promising system for the manipulation of micro-nano particles and fluids. In this platform, alternating current (AC) electric field is usual an effective tool for the general particle control. However, traditional work paid more attention on the regular spherical particles with no significant distinction when rotating, resulting in imprecise rotation speed calculation.In essence, non-spherical especially biocompatible particles are not only important for biology application but also significant for obtaining accurate rotating results .ence, in this paper, SU-8, one of the most biocompatible materials was selected as the manipulated object. AC electric field is employed to rotate SU-8 microrods, in order to obtain controllable rotation angle for both the accurate experimental results and biosensor applications. Firstly, Clausius- Mossotti (CM) factors frequency spectra with different surface conductance and medium conductivities are presented, thus the theoretical formula is carried out, including both the torque and rotation velocity expressions of SU-8 microrods.Moreover, simulations for the electric field distribution are developed, indicating the rotating field. Secondarily, the quadrupole electrodes are used to generate rotating electric field, and the electrorotation of SU -8 microrods in different medium is carried out, showing that the particles rotate in the opposite direction of the electric field, meanwhile, the peak frequency increases with the conductivity increase. Finally, the experimental results are discussed and compared with theoretical analysis, and the comparison result shows that they have a good agreement.This work proposes an effective and controllable method to rotate microrods, showing extend application potentials in microelectronics and biosensors.