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本临床研究共设4组:对照组(n=30);饮食和运动治疗组(n=28);拜唐苹治疗组(n=29);文迪雅治疗组(n=32)。观察时间为6个月。饮食加运动组按个体情况安排饮食及运动方案,每月重复宣教饮食及运动的治疗意义;拜唐苹50mg每日3次,文迪雅4mg每日1次。结果:对照组治疗后,体重指数(BMI)、空服血糖(FPG)、餐后2h血糖(PPG)、总胆固醇(TC)、甘油三脂(TG)、低密度脂蛋白胆固醇(LDL)、空腹胰岛素(FInS)等有上升趋势,但无统计学差异(P>0.05)。饮食加运动治疗组,上述各指标有不同程度下降(P>0.05)。拜唐苹治疗组和文迪雅治疗组各指标,明显下降,具有统计学差异(P<0.01)。后高密度脂蛋白胆固醇(HDL)(P>0.05)。结论:对IGT患者在饮食,运动的基础上有必要给予拜唐苹、文迪雅等药物干预治疗。
There are 4 groups in this clinical study: control group (n = 30), diet and exercise group (n = 28), Baitangping treatment group (n = 29) and Avandia treatment group (n = 32). Observation time was 6 months. Diet plus exercise group arranged diet and exercise programs according to individual circumstances, repeated monthly mission education and exercise treatment significance; Tang Tang Ping 50mg 3 times a day, Avandia 4mg daily. Results: The body mass index (BMI), FPG, PPG, TC, TG, LDL, Fasting insulin (FInS) and so on have an upward trend, but no statistical difference (P> 0.05). Diet plus exercise treatment group, the above indicators have decreased to varying degrees (P> 0.05). The indexes of Tangtangping treatment group and Avandia treatment group obviously decreased, with statistical difference (P <0.01). After high-density lipoprotein cholesterol (HDL) (P> 0.05). Conclusion: It is necessary to treat patients with IGT on the basis of diet and exercise.