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目的:探讨阿奇霉素在儿科临床应用中的不良反应及其对策。方法:随机选取2015年2月~2016年2月来我院儿科治疗的患儿260例,随机均分为两组,每组130例,将第一组设为甲组,采用静脉注射阿奇霉素的方法对患儿进行治疗;将第二组设为乙组,采用口服阿奇霉素的方式对患儿进行治疗,治疗一段时间后,观察和记录两组患儿的临床不良反应,并进行分析研究。结果:比较和分析两组患者的临床记录,对其所发生的不良反应进行统计,常见的不良反应主要有发热、过敏性皮疹、过敏性休克及胃肠道反应等,比较两组患儿不良反应的发生率,无显著差异性,无统计学意义(P>0.05)。结论:儿科临床应用中采用阿奇霉素进行治疗,易发生不良反应,主要有过敏性休克、发热、过敏性皮疹及胃肠道反应等,临床治疗期间,给予及时的处理方案,采取有效的预防措施,有利于缓解症状,避免不良事件的发生,具有重要的临床价值,值得推广和应用于临床。
Objective: To investigate the adverse reactions of azithromycin in pediatric clinical application and its countermeasures. Methods: From February 2015 to February 2016, 260 children with pediatric treatment in our hospital were randomly selected and randomly divided into two groups (130 cases in each group). The first group was set as Group A, and the patients were given intravenous azithromycin Methods The second group was set as group B, the patients were treated with oral azithromycin. After treatment for a period of time, the clinical adverse reactions of the two groups were observed and recorded and analyzed. Results: The clinical records of two groups were compared and analyzed. The adverse reactions were statistically analyzed. The common adverse reactions were fever, allergic rash, anaphylactic shock and gastrointestinal reactions. The incidence of reaction, no significant difference, no statistical significance (P> 0.05). Conclusion: In pediatric clinical use of azithromycin for treatment, prone to adverse reactions, mainly anaphylactoid shock, fever, allergic rash and gastrointestinal reactions, etc., during the clinical treatment, to give timely treatment options and take effective preventive measures, Help to relieve symptoms and avoid the occurrence of adverse events, has important clinical value, it is worth to promote and apply in clinical.