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目的 :测定胃癌患者和正常人 (各 60例 )的血浆同型半胱氨酸水平 ,以探讨血浆同型半胱氨酸与胃癌的关系 ;方法 :正常对照者来自本院体检 40岁以上者 ,胃癌患者经电子胃镜及病理确诊 ,血浆同型半胱氨酸采用高效液相色谱法测定 ;结果 :胃癌患者同型半胱氨酸 ( 1 8.85± 7.93 )显著高于正常人 ( 1 1 .84± 2 .3 9) ,两组之间存在着极其显著性差异 (P<0 .0 0 1 ) ;结论 :人血浆同型半胱氨酸在胃癌及胃癌前期病变 (胃粘膜萎缩、生化及不典型增生 )过程中起着重要的作用
Objective: To determine plasma homocysteine levels in gastric cancer patients and normal subjects (60 cases each) to explore the relationship between plasma homocysteine and gastric cancer.Methods: Normal control subjects were from our hospital for over 40 years old, with gastric cancer The patients were diagnosed by electronic endoscopy and pathology, plasma homocysteine was determined by high performance liquid chromatography. Results: Homocysteine (1 8.85 ± 7.93) in patients with gastric cancer was significantly higher than that in normal people (11.84 ± 2. 3 9). There was an extremely significant difference between the two groups (P0.01). Conclusion: Plasma homocysteine levels in gastric cancer and gastric precancerous lesions (gastric mucosal atrophy, biochemical and atypical hyperplasia) The process plays an important role