Understanding human diseases with high-throughput quantitative measurement and analysis of molecular

来源 :中国科学:生命科学英文版 | 被引量 : 0次 | 上传用户:jhl1989
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Microarray and deep sequencing technologies have provided unprecedented opportunities for mapping genome mutations,RNA transcripts,transcription factor binding,and histone modifications at high resolution at the genome-wide level.This has revolutionized t
其他文献
The 2018 Nobel Prize in Physiology or Medicine was awarded to both Professors James P.Allison and Tasuku Honjo for their“discovery of cancer therapy by inhibit
Many receptors,including thermal receptors and mechanical receptors,are only activated by stimuli within a clearly defined range of intensities.Differences in t
Due to the low number of collectable stem cells from single umbilical cord blood(UCB)unit,their initial uses were limited to pediatric therapies.Clinical applic
<正>Dear Editors,Sexual dimorphism is the systematic difference in size,shape,color,physiology,and behavior,between male and female individuals of the same spec
Previous studies indicate that emotion regulation may occur unconsciously, without the cost of cognitive effort, while conscious acceptance may enhance negative
期刊
<正>Mammalian Sirtuins are the homologs of yeast Saccharomyces cerevisiae Sir2(silen t information regulator 2),which functions in chromatin silencing to preven
This study analyzes change in carbon storage by applying forest growth models and final cutting age to actual and potential forest cover for six major tree spec
<正>West African countries are currently suffering the most severe pandemic of Ebola virus disease ever recorded,with4269 human cases and 2288 deaths(through 6
The perception of pain involves the activation of the spinal pathway as well as the supra-spinal pathway,which targets brain regions involved in affective and c