论文部分内容阅读
铊是一种剧毒高危的重金属,毒性高于铅和汞,具有蓄积性[1]。通常经呼吸道、消化道和皮肤吸收,对肝脏、肾脏等器官造成慢性损害。当人体摄入过量的铊时,会引起急性中毒,发生脱发等一系列病症[2,3]。目前,国内外有关慢性铊中毒的报道主要为误食以及投毒的急性铊中毒等事件。铊进入体内后,几乎全部经尿液排泄,因此尿铊含量的高低可直接反映铊的接触水平和中毒情况。为了解尿液基体对实验的干扰,提高方法的灵敏度、准确性,现进行如下实验研究。
Thallium is a highly toxic heavy metal, toxic higher than lead and mercury, with accumulation [1]. Usually through the respiratory tract, digestive tract and skin absorption, causing chronic damage to the liver, kidneys and other organs. When the body excessive intake of thallium, it can cause acute poisoning, hair loss and a series of other conditions [2,3]. At present, the reports of chronic thallium poisoning both at home and abroad are mainly the incidence of acute thallium poisoning and poisoning. Thallium into the body, almost all excreted by the urine, so the level of urinary thallium can directly reflect the level of exposure to thallium and poisoning. In order to understand the interference of the urine matrix on the experiment and improve the sensitivity and accuracy of the method, the following experimental research is carried out.