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目的分析厦门地区尿碘含量与甲状腺结节患病率的关系。方法采用分层整群抽样法,对277名年龄20~69岁的厦门市海边、海岛、山区居民进行甲状腺检查和尿碘检测,并进行统计分析。结果甲状腺结节患病率48.4%(134/277),海岛55.6%(55/99)、海边50.0%(42/84)和山区39.7%(37/94),三者差异无统计学意义;女性患病率(54.8%)高于男性(40.2%);患病率随年龄增长而上升。尿碘中位数175.20μg/L,海岛241.40μg/L>海边173.25μg/L>山区129.35μg/L;甲状腺结节病例组与正常组比较,尿碘(中位数)差异无统计学意义。结论厦门地区人群尿碘水平处于适宜水平,未发现居民尿碘水平与甲状腺结节患病率存在明显关系,甲状腺结节患病率与性别和年龄相关。
Objective To analyze the relationship between urinary iodine content and the prevalence of thyroid nodules in Xiamen area. Methods A stratified cluster sampling method was used to detect thyroid and urinary iodine in 277 residents of the seaside, islands and mountainous areas in Xiamen City, aged from 20 to 69 years. Statistical analysis was made. Results The prevalence of thyroid nodules was 48.4% (134/277), 55.6% (55/99) in islands, 50.0% (42/84) in seaside and 39.7% (37/94) in mountain areas. There was no significant difference among the three groups. The prevalence of women (54.8%) was higher than that of men (40.2%); the prevalence rose with age. The urinary iodine median (175.20μg / L, island 241.40μg / L> seaside 173.25μg / L> mountain 129.35μg / L); thyroid nodules cases group compared with the normal group, urinary iodine (median) was no significant difference . Conclusion The urinary iodine level in Xiamen population is at an appropriate level. There is no obvious relationship between urinary iodine levels and the prevalence of thyroid nodules. The prevalence of thyroid nodules is related to gender and age.