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1例57岁女性肺癌患者,给予注射用脂溶性维生素(Ⅱ)10 ml+0.9%氯化钠注射液250 ml静脉滴注,滴速60滴/min。用药约1 min后,患者出现麻木,抽搐,意识不清,全身发红,口唇发绀。立即停药,静脉推注肾上腺素0.5 mg、地塞米松10 mg、多巴胺40 mg,予鼻导管吸氧。5 min后患者神志转清,心电监护示心率127次/min,血氧饱和度0.85,血压测不出。继续给予多巴胺200 mg加入0.9%氯化钠注射液50 ml静脉泵入,肾上腺素2 mg加入0.9%氯化钠注射液50 ml静脉泵入,0.9%氯化钠注射液500 ml及右旋糖酐40注射液500 ml静脉滴注。2 h后患者血压80/50 mm Hg(1 mm Hg=0.133 kPa)。3 h后血压升至130/70 mm Hg,血氧饱和度0.98,过敏症状消失。
A 57-year-old woman with lung cancer was given intravenous infusion of 10 ml fat-soluble vitamin (10 ml + 0.9% sodium chloride injection 250 ml / min. About 1 min after treatment, patients with numbness, convulsions, unconsciousness, body redness, lips cyanosis. Immediate withdrawal, intravenous injection of epinephrine 0.5 mg, dexamethasone 10 mg, dopamine 40 mg, nasal catheter oxygen. 5 min after the patient consciousness clear, ECG heart rate showed 127 beats / min, oxygen saturation of 0.85, blood pressure can not be measured. Continue to give dopamine 200 mg 0.9% sodium chloride injection 50 ml intravenously, 2 mg of epinephrine plus 0.9% sodium chloride injection 50 ml intravenously, 0.9% sodium chloride injection 500 ml and dextran 40 injection 500 ml intravenous drip. After 2 hours, the patient’s blood pressure was 80/50 mm Hg (1 mm Hg = 0.133 kPa). Blood pressure rose to 130/70 mm Hg after 3 hours, and oxygen saturation was 0.98. The symptoms of allergy disappeared.