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目的探讨抗毒补心胶囊治疗小儿病毒性心肌炎的临床疗效及对患儿免疫功能的影响。方法将110例病毒性心肌炎患儿采用随机数字表法分为对照组和治疗组,各55例。对照组采取常规支持治疗,治疗组在对照组基础上加用抗毒补心胶囊,观察2组临床疗效及免疫功能各项指标的变化。结果治疗组总有效率为92.73%,对照组为69.09%,2组比较差异有统计意义(P<0.05);治疗后2组患儿心肌酶各项指标均较治疗前明显降低,2组比较差异有统计意义(P<0.05);治疗组治疗后CD3+,CD4+和CD4+/CD8+均显著低于治疗前及对照组治疗后(P<0.05)。结论抗毒补心胶囊治疗小儿病毒性心肌炎疗效明显,可改善患儿免疫功能,具有较好的临床应用和推广价值。
Objective To investigate the clinical efficacy of Kangdu Buxin Capsule in treating children with viral myocarditis and its effect on immune function in children. Methods A total of 110 children with viral myocarditis were divided into control group and treatment group by random number table method, 55 cases each. Control group to take conventional supportive treatment, the treatment group on the basis of the control group with anti-drug Buxin capsules, observed two groups of clinical efficacy and immune function changes in various indicators. Results The total effective rate was 92.73% in the treatment group and 69.09% in the control group, with significant difference between the two groups (P <0.05). The indexes of myocardial enzymes in the two groups were significantly lower than those before treatment (P <0.05). The levels of CD3 +, CD4 + and CD4 + / CD8 + in the treatment group were significantly lower than those before treatment and in the control group after treatment (P <0.05). Conclusion Anti-drug Buxin Capsule treatment of children with viral myocarditis obvious effect, can improve children’s immune function, has good clinical application and promotion value.