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据中新网(广州)10月13日消息报道,广州中山大学中瘤组织并抑制肿瘤生长,正常器官则不受影响。除细胞水平山医学院颜光美教授课题组研究发现天然病毒M1能选择性及动物实验之外,课题组还采用临床标本离体活组织培养模地感染并杀伤包括肝癌、结直肠癌、膀胱癌、黑色素瘤在内的型进一步证实了上述新型溶瘤病毒的有效性和特异性。据多种体外培养的癌细胞,而对正常细胞无毒副作用。整体动悉,该研究成果对阐明新型天然溶瘤病毒M1选择性杀伤肿物实验结果显示,经尾静脉注射的M1病毒能显著富集在肿瘤细胞的机制和研发新型靶向抗肿瘤药物都具有重要意义。
According to the news report from Zhongxinwang (Guangzhou) on October 13, Sun Yat-sen University in Guangzhou organized tumors and inhibited tumor growth. Normal organs were not affected. In addition to the cell level mountain medical college Yan Guangmei research group found that the natural virus M1 can be selective and animal experiments, the research group also used clinical specimens in vitro tissue culture mold infection and killing, including liver cancer, colorectal cancer, bladder cancer, The type of melanoma further confirms the validity and specificity of the novel oncolytic viruses described above. According to a variety of in vitro cultured cancer cells, and normal cells without toxic side effects. Overall, the results of this study to elucidate the new natural oncolytic virus M1 selective killing tumor results show that via the tail vein injection of M1 virus can significantly enrich the mechanism of tumor cells and the development of new targeted antitumor drugs have Significance.