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目的观察滤出白细胞技术应用于输血的临床效果分析。方法回顾性选取2016年5月~2017年5月我院收治的进行输血检测的患者86例,据血液提取方式不同分两组,对照组采取红细胞常规输血,实验组施行过滤白细胞技术输血,分析两组患者输血期间相关指标与不良反应情况。结果研究组滤除后的血小板(31.82±12.45)×10~9/L、血红蛋白(129.29±13.58)g/L与白细胞(0.10±0.07)×10~9/L相比对照组计数低(P<0.05);研究组体温升值(0.47±0.57)℃、FIB(2.41±0.35)g/L、PT(12.01±0.46)s、APTT(38.62±4.45)s与TT(18.64±1.83)s均优于对照组各项指标(P<0.05);研究组发热2例、蛋白尿1例与过敏1例,研究组输血后不良反应发生率9.30%(4/43)相比对照组30.23%(13/43)的概率低(P<0.05)。结论输血时滤出白细胞技术有益于减少输血者的不良反应,改善各项凝血指标,降低血浆中纤维蛋白原,值得广泛运用。
Objective To observe the clinical effect of leukocyte filtration in transfusion. Methods Retrospectively selected from May 2016 to May 2017 in our hospital for transfusion testing of 86 patients, according to the method of blood extraction divided into two groups, the control group to take RBC routine blood transfusion, the experimental group were performed leukocyte transfusion, analysis Two groups of patients during transfusion related indicators and adverse reactions. Results The platelet count (31.82 ± 12.45) × 10 ~ 9 / L and the hemoglobin (129.29 ± 13.58) g / L in the study group were significantly lower than those in the control group (P <0.01 ± 0.07) × 10 ~ 9 / L <0. 05). The body temperature rise (0.47 ± 0.57) ℃, FIB (2.41 ± 0.35) g / L, PT (12.01 ± 0.46) s, APTT (38.62 ± 4.45) s and TT (P <0.05). There were 2 cases of fever, 1 case of proteinuria and 1 case of allergy in the study group. The incidence of adverse reactions in the study group was 9.30% (4/43) compared with that in the control group (30.23%, 13 / 43) (P <0.05). Conclusions Leukocyte filtration during blood transfusion is beneficial to reduce the adverse reactions of blood transfusion, improve various coagulation indexes and reduce fibrinogen in plasma, which deserves wide application.