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用免疫球蛋白(Ig)预防暴露前后甲型肝炎病毒(HAV)感染的保护期仅为4～6个月。本文比较了单剂和加强剂量甲型肝炎灭活疫苗(iHAV)与单剂Ig在成人中的安全性、耐受性及免疫原性。
The protection of Hepatitis A virus (HAV) infection with immunoglobulin (Ig) before and after exposure is only 4 to 6 months. This article compares the safety, tolerability and immunogenicity of iHAV and single-dose Ig in adults with single-dose and booster doses of hepatitis A vaccine.