患者甘××,男,47岁,住院号294575,因黄疽、腹胀、皮肤色素沉着6年、加重2月、少尿1月,于1986年3月12日入院。患者1975年出现颈前部肿大,食欲亢进,多汗怕热,诊断为“甲状腺机能亢进”(甲亢)。1978年10月和1979年6月服“~(131)Ⅰ”后,甲状腺缩小,症状改善。1979年底患者渐起巩膜黄染,腹胀,纳差,间常心悸和双下肢浮肿,并发现皮肤色素沉着,以双膝以下明显,呈棕褐色,伴性欲减退,体重减轻。当时发现“肝大、质硬”,曾疑肝癌,但 AFP 为阴性。1980年至1982年因全身浮肿住他院,诊断为“甲亢,心 Patients Gan × ×, male, 47 years old, hospital number 294575, due to jaundice, bloating, skin pigmentation for 6 years, increased in February, oliguria in January, on March 12, 1986 admission. Patients with neck anterior enlargement in 1975, hyperactive appetite, sweating afraid of heat, diagnosed as “hyperthyroidism” (hyperthyroidism). In October 1978 and June 1979 after serving “~ (131) Ⅰ”, the thyroid shrinks, the symptoms improve. By the end of 1979, the patient developed scleral yellow dye, abdominal distension, anorexia, inter-normal palpitations, and edema of both lower extremities. Pigmentation of the skin was found to be noticeable below the knees with tan, with loss of libido and weight loss. At that time found that “liver, hard,” had suspected liver cancer, but AFP was negative. From 1980 to 1982 due to systemic edema in his hospital, diagnosed as "hyperthyroidism, heart