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目的分析丁苯酞联合舒血宁注射液改善脑卒中患者血清水平及神经功能的效果。方法采用随机数字表法将97例脑卒中患者进行分组,对照组48例给予丁苯酞软胶囊治疗,观察组49例给予丁苯酞软胶囊联合舒血宁注射液治疗。观察两组患者治疗后的神经功能及血清指标改善水平,并进行对比。结果观察组治疗后血清超氧化物歧化酶(SOD)(98.96±13.49)U/ml,血清丙二醛(MAD)(5.09±0.84)nmol/ml,效果优于对照组[(81.27±12.11)U/ml,(6.94±1.22)nmol/ml,P<0.05];观察组治疗后美国国立卫生研究院卒中量表(NIHSS)评分[(14.89±3.01)分]低于对照组[(18.98±3.05)分,P<0.05]。结论采用丁苯酞联合舒血宁注射液通过活血化瘀,抑制氧自由基,减少谷氨酸,改善脑卒中患者血清水平及神经功能,效果确切,值得临床推广及应用。
Objective To analyze the effects of butylphthalide and shuxuening injection on the serum level and neurological function in patients with stroke. Methods A random number table was used to divide 97 stroke patients. The control group was treated with butylphthalide soft capsule. In the observation group, 49 patients were given butylphthalide soft capsule combined with Shuxuening injection. After treatment, the neurological function and the serum level of the two groups were observed and compared. Results The serum levels of superoxide dismutase (SOD) (98.96 ± 13.49) U / ml and serum malondialdehyde (MAD) (5.09 ± 0.84) nmol / ml in the observation group were better than those in the control group [(81.27 ± 12.11) (6.94 ± 1.22) nmol / ml, P <0.05]. The NIHSS score [(14.89 ± 3.01)] in the observation group was significantly lower than that in the control group [(18.98 ± 3.05) points, P <0.05]. Conclusion The combination of Butylphthalide and Shuxuening Injection can promote the blood circulation and blood circulation, inhibit the oxygen free radicals, reduce glutamate, and improve the serum level and nerve function of patients with stroke. It is worthy of clinical promotion and application.