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目的探讨中山地区宫颈癌及癌前病变筛查TCT结果和流行病学情况。方法 2011年3月-2013年12月对中山市130 475例已婚妇女采用液基薄层细胞学(TCT)和新柏氏电脑辅助阅片系统(TIS)进行检测,将ASCUS/AGC以上病变列为TCT阳性病例并进行阴道镜下多点活检作进一步确诊,并对其危险因素进行分析。结果 TCT总阳性率4.29%,宫颈癌检出率为38/10万(50/130 475)。单因素分析结果显示:筛查者的年龄、初次性生活年龄、文化程度、职业、绝经、工具避孕等因素与TCT阳性率有关;多因素分析结果显示:年龄、文化程度、职业和绝经差异仍然有统计学意义(P<0.05),提示其为TCT阳性率的独立影响因素。结论中山地区宫颈癌发生率较高,年龄、文化程度、职业、绝经、工具避孕等因素与TCT阳性率有关,对当地妇女进行个人健康教育及宫颈癌防治知识宣传是预防宫颈癌和癌前病变的重要措施和保障。
Objective To investigate the results of TCT screening and epidemiology of cervical cancer and precancerous lesions in Zhongshan area. Methods From March 2011 to December 2013, 130 475 married women in Zhongshan City were tested by liquid-based thin-layer cytology (TCT) and New Computer’s Computerized Tissue Assisted Reading System (TIS). The ASCUS / AGC lesions For TCT-positive cases and colposcopy biopsy for further diagnosis, and its risk factors were analyzed. Results The total positive rate of TCT was 4.29%, and the detection rate of cervical cancer was 38/10 (50/130 475). The results of univariate analysis showed that the age, initial sex, educational level, occupation, menopause, tool contraception and other factors were related to the positive rate of TCT. The results of multivariate analysis showed that age, education level, occupational and menopausal differences There was statistical significance (P <0.05), suggesting that it is an independent factor of TCT positive rate. Conclusions The incidence of cervical cancer in Zhongshan area is high. The factors such as age, education level, occupation, menopause and tool contraception are related to the positive rate of TCT. Knowledge of local health education and prevention of cervical cancer is the prevention of cervical cancer and precancerous lesions Important measures and protection.